Immunohistochemistry - Progesterone Receptor (PR)
- Introduction to PR
PR or Progesterone receptor, is one of the most widely used antibodies in Immunohistochemistry.
Picture 1 – PR positivity
This antibody is mainly used along with ER and Her2 to assist in determination of whether a breast case will respond to treatment based on the levels of positivity. This stains up the nuceli of breast epithelial cells and some carcinomas that are PR+. It labels epithelial cells of breast, ovary and endometrium.